2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-151965
    Antimalarial agent 18
    		Inhibitor
    Antimalarial agent 18 is an potent antimalarial agent, based on electronic, highly lipophilic and siderophoric properties. Antimalarial agent 18 belongs to acyloxymethyl series, as a fosmidomycin surrogate, which is potent IspC inhibitor against the non-mevalonate isoprenoid biosynthesis pathway. Antimalarial agent 18 inhibits P. falciparum (IC50=50 nM) and A. baumanii (IC50=390 nM).
    Antimalarial agent 18
  • HY-161309
    RUPB-61
    		Inhibitor
    RUPB-61 is a potent Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) inhibitor with an IC50 value of 13 nM. RUPB-61 shows antiparasitic activity.
    RUPB-61
  • HY-N0352R
    Tuberostemonine (Standard)
    		Inhibitor
    Tuberostemonine (Standard) is the analytical standard of Tuberostemonine. This product is intended for research and analytical applications. Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity Ferredoxin-NADP+ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine has a level of activity as a feeding deterrent .
    Tuberostemonine (Standard)
  • HY-N0059R
    D-Arabinose (Standard)
    		Inhibitor
    D-Arabinose (Standard) is the analytical standard of D-Arabinose. This product is intended for research and analytical applications. D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose (Standard)
  • HY-N13197
    6-Methyl-5,6-dihydro-2H-pyran-2-one
    		Inhibitor
    6-Methyl-5,6-dihydro-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities.
    6-Methyl-5,6-dihydro-2H-pyran-2-one
  • HY-N15748
    Pelorol
    		Inhibitor
    Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC50 of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria.
    Pelorol
  • HY-N10928
    Lettowienolide
    		Inhibitor
    Lettowienolide, a geranylbenzoquinonoid, exhibits mild in vitro activity against the Plasmodium falciparum malaria parasite (IC50~20 μg/mL).
    Lettowienolide
  • HY-12643R
    Eprinomectin (Standard)
    		Inhibitor
    Eprinomectin (Standard) is the analytical standard of Eprinomectin. This product is intended for research and analytical applications. Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity.
    Eprinomectin (Standard)
  • HY-118865
    Piperaquine tetraphosphate
    		Inhibitor
    Piperaquine tetraphosphate is a potent antimalaria agent. Piperaquine tetraphosphate shows inhibition for chloroquine-sensitive and the chloroquine-resistant isolates. Piperaquine tetraphosphate in combination with dihydroartemisinin has the potential for the research of chloroquine-resistant malaria.
    Piperaquine tetraphosphate
  • HY-P5694
    Human α-defensin 5
    		Inhibitor
    Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC50: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity.
    Human α-defensin 5
  • HY-N1924R
    Crassicauline A (Standard)
    		Inhibitor
    Crassicauline A (Crassicaulin A) Standard is the analytical standard of Crassicauline A (HY-N1924). This product is intended for research and analytical applications. Crassicauline A (Crassicaulin A) is a diester-type diterpenoid alkaloid. Crassicauline A exhibits feeding deterrent activity against adult Tribolium castaneum, with a EC50 of 1134.5 ppm. Crassicauline A induces arrhythmia at a dose of 0.10 mg/kg.
    Crassicauline A (Standard)
  • HY-147933
    Antitrypanosomal agent 8
    		Inhibitor
    Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM).
    Antitrypanosomal agent 8
  • HY-149939
    Antimalarial agent 26
    		Inhibitor
    Antimalarial agent 26 is an orally active 1,4-naphthoquinones derivative with antimalarial activities. Antimalarial agent 26 shows cytotoxicity against P. falciparum and selectivity over mammalian cell lines. Antimalarial agent 26 inhibits P. burghei induced parasitemia in vivo.
    Antimalarial agent 26
  • HY-155301
    Antileishmanial agent-24
    		Inhibitor
    Antileishmanial agent-24 (compound 33) is an antileishmanial agent with an IC50 of 5.39 μM against amastigote.
    Antileishmanial agent-24
  • HY-146044
    Antiparasitic agent-6
    		Inhibitor
    Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC50 = 13.64 μM).
    Antiparasitic agent-6
  • HY-119688
    Amabiline
    		Inhibitor
    Amabiline is a compound isolated from a plant that contains a variety of bioactive ingredients including Amabiline. The plant as a whole has a variety of traditional uses and also has certain pharmacological activity and toxicity.
    Amabiline
  • HY-144294
    Purine phosphoribosyltransferase-IN-1
    		Inhibitor
    Purine phosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of the Plasmodium falciparum (Pf), P. vivax (Pv) and Trypanosoma brucei (Tbr) 6-oxopurine purine phosphoribosyltransferases (PRTs), with Ki values of 50, 20, and 2 nM, respectively.
    Purine phosphoribosyltransferase-IN-1
  • HY-158776
    SLU-10482
    		Inhibitor
    SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM.
    SLU-10482
  • HY-168862
    Insecticidal agent 18
    		Inhibitor
    Insecticidal agent 18 (compound 34) is a potent insecticidal agent. Insecticidal agent 18 shows acaricidal activity.
    Insecticidal agent 18
  • HY-101660
    Nifursemizone
    		Inhibitor 99.25%
    Nifursemizone is an antiprotozoal agent.
    Nifursemizone
Parasite Isoform Comparison

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